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Metabolic dysfunction associated steatotic liver disease (MASLD) in children: use of FibroScan
- Caitlin MurphyKing's College Hospital
Key points
- FibroScan is a non-invasive marker of steatosis and fibrosis in children, and its results were correlated with blood tests, BMI and ultrasound findings in 76 children.
- There was a significant correlation between BMI and both fibrosis and steatosis.
- MASLD is for the most part a reversible disease, so identification is a good time to intervene.
Caitlin Murphy, King's College Hospital, discusses her work in identifying identifying fibroscan markers of liver stiffness and steatosis, with anthriopometry, ultrasound and biochemical liver functions tests in 76 children with MASLD. The majority of children were found to have evidence of significant steatosis and mild fibrosis, both of which are completely reversible at the stage of identification. This interview took place at the RCPCH conference 2024 in Birmingham, UK.
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Automatic transcript, lightly edited for readability. It may contain errors, so check it against the video before quoting.
So our study, our poster, is about metabolically associated liver disease in children. We helped in a clinic where we perform FibroScans, and a FibroScan is a non-invasive marker of steatosis and fibrosis in children, and it looks at their liver and also their spleen size. We correlated the results of the FibroScan with other biomarkers such as blood tests, BMI and ultrasound findings.
We looked at 76 children and we found a significant correlation between BMI and fibrosis and steatosis, and found a correlation between ultrasound findings of steatosis on the liver and also fibrosis scores and steatosis scores on their FibroScan. We found that a high FibroScan correlated with higher ALT markers and ultrasound findings. We identified that this would be a perfect time to intervene, because for the most part MASLD is a reversible disease, but can have a high disease burden if not treated appropriately at the right time.
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Cite this video
Caitlin Murphy. “Metabolic dysfunction associated steatotic liver disease (MASLD) in children: use of FibroScan.” The Paediatric Video Journal, 30 December 2024. https://paediatricvj.com/videos/metabolic-dysfunction-associated-steatotic-liver-disease-masld-murphy/
This interview is educational content intended for healthcare professionals and is not medical advice. Views expressed are those of the speaker. © The Paediatric Video Journal. All rights reserved.